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Advantages of optical rotation analyzer

2025-03-21

Optical rotation analyzers, especially those represented by polarimeters, show significant advantages in several fields. The following analysis is carried out from the dimensions of accuracy, function, efficiency and stability:

1. High precision and sensitivity

Core performance: The minimum reading of modern polarimeter (such as JH-P400 type) can reach 0.001°, the indicating error is controlled at ±0.01°——±0.02°, and the repeatability standard deviation is 0.002°.

Application scenario:

Pharmaceutical industry: Precise measurement of the rotation of chiral drugs to ensure that the enantiomer excess (ee value) meets the standard (e.g., >99% purity for some drugs)。

Chemical analysis: Monitoring small changes in rotation during the reaction and inferring molecular configuration transformation.

 

2. Multi-domain applicability

Pharmaceutical: Verify the optical purity of the drug to ensure the correct structure of the active ingredient.

Food: Detect the concentration and type of sugar solution (such as distinguishing fructose and glucose) to control the sweetness of food.

Environmental monitoring: The detection of chiral pollutants (such as pesticides) in water is more sensitive than traditional spectrophotometry.

Materials science: Analysis of molecular orientation of materials such as liquid crystals and optical films.

 

3. Automation and intelligence

Functional integration:

Temperature control: Some instruments support 15℃——30℃ temperature control, accuracy ±0.2℃, eliminate temperature interference.

Data storage: can store 1000 groups of data, support USB export, easy to trace analysis.

Automatic calibration: Built-in multi-point calibration program to reduce human error.

Improved efficiency: The automatic measurement process shortens the experiment cycle and is suitable for batch sample analysis.

 

4. Structural stability and durability

Optical design: LED cold light source + high-precision interference filter, high wavelength stability.

Mechanical characteristics: no vulnerable rotating parts (such as the motor of the traditional laser caliper), life of more than 8 years, maintenance only needs to clean the optical components.

 

5. Real-time dynamic measurement capability

High frequency response: such as photoelectric rotary caliper, measuring frequency up to 2000Hz, 2000 data points per second acquisition.

Industrial adaptation: suitable for 60rpm high speed production line, can measure complex cross section materials (such as rebar), blind area ≤100mm.

 

6. Anti-interference and environmental adaptability

Light source technology: The use of 520nm green fixed wavelength, anti-light, dust, temperature fluctuations interference.

Dynamic compensation: electronic shutter and multi-channel synchronization technology to eliminate the effect of the measured object jitter.

 

​7. Compliance and standardization

Industry certification: comply with GMP and other quality specifications to ensure pharmaceutical production process compliance.

International benchmarking: such as TORNOS Faraday rotator up to 60dB isolation, suitable for high-end laser systems.

 

Sum up

The optical rotation analyzer has become a key analytical tool in pharmaceutical, food, chemical, material science and other fields through its advantages of high accuracy, multi-scene adaptation, automated design and stability. Its technological evolution (such as digital measurement, intelligent calibration) has further consolidated its irreplaceability in industry and research.
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